The Huffington Post has an interesting set of maps that shows how the U.S. South fares in regards to poverty, minimum wage, economic mobility, health care coverage, health issues, teen pregnancy, and overall happiness.
In comparison to the U.S. overall, the South is at a disadvantage in many of these areas.
U.S. state life expectancy compared to countries around the world [map]
Over at the Atlantic, there is an interesting map [not the one to the right in this article]. It compares the life expectancy in U.S. states and imposes the the names of countries around the world with a similar life expectancy onto the respective state. Thus, Mississippi becomes Syria (75 years and I am not sure whether this takes into account the ongoing bloody civil there) and California becomes Liechtenstein (81 years).
The best thing about the map: You can go to http://www.measureofamerica.org/maps/, a project of the Social Science Research Council, and see how well individual states fare by a variety of measures, such as the Human Development Index (HDI), education, health, or income.